1-[4-(trifluoromethyl)phenyl]butane-1,3-dione

1-[4-(trifluoromethyl)phenyl]butane-1,3-dione - Names and Identifiers

Name	1-[4-(trifluoromethyl)phenyl]butane-1,3-dione
Synonyms	1-(4-TRIFLUOROMETHYLPHENYL)BUTANE-1,3-DIONE 1-(4-Trifluoromethylphenyl)butane-1,3-dione 1-[4-(trifluoromethyl)phenyl]butane-1,3-dione 1-[4-(TrifluoroMethyl)phenyl]-1,3-butanedione 1,3-Butanedione,1-[4-(trifluoromethyl)phenyl]-
CAS	258346-69-9
InChI	InChI=1/C11H9F3O2/c1-7(15)6-10(16)8-2-4-9(5-3-8)11(12,13)14/h2-5H,6H2,1H3

1-[4-(trifluoromethyl)phenyl]butane-1,3-dione - Physico-chemical Properties

Molecular Formula	C11H9F3O2
Molar Mass	230.18
Density	1.247g/cm³
Boling Point	287.669°C at 760 mmHg
Flash Point	101.294°C
Vapor Presure	0.002mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.46

1-[4-(trifluoromethyl)phenyl]butane-1,3-dione - Introduction

1-[4-(trifluoromethyl)phenyl]butane-1,3-dione, also known as 1-[4-(trifluoromethyl)phenyl]-1, 3-butanone, it is an organic compound. Its structural formula is C10H9F3O2.

In terms of properties, this compound is a solid with a white or off-white appearance. It is stable at room temperature and is not volatile. Its melting point is usually between 60-65°C and its boiling point is about 180°C. It can be dissolved in some organic solvents, such as ethanol and dimethylformamide.

This compound has certain application value in the field of chemistry and medicine. It can be used as a reagent and intermediate in organic synthesis reactions, for example as a starting material for the preparation of other organic compounds. It can also be used in drug synthesis, for example as a precursor of a drug or as a radical of an active moiety of a synthetic drug.

In terms of preparation, 1-[4-(trifluoromethyl)phenyl]butane-1,3-dione can be synthesized through various reaction pathways. One common method is to react the known compound ethyl 4-(trifluoromethyl) benzoate with 1,3-butanedione under basic conditions to yield the desired product. This synthetic route usually requires some organic reagents and solvents.

In terms of safety information, when handling this compound, care needs to be taken to prevent contact with the skin and inhalation of its dust. It may have certain risks to health, so it needs to be operated under proper ventilation conditions and wear appropriate personal protective equipment. During use and storage, avoid contact with oxidants and heat sources to avoid generating harmful gases or vapors. Disposal of waste shall comply with relevant local laws and regulations.

Last Update：2024-04-10 22:30:50